Papers
In the Spotlight
Browse the lab's key research findings.
Cortical somatostatin LRP neurons and interneurons exhibit divergent developmental trajectories
Fisher et al. (Neuron, 2023)
Optimization of interneuron function by direct coupling of cell migration and axonal targeting
Lim et al. (Nature Neuroscience, 2018)
Early emergence of cortical interneuron diversity in the mouse embryo
Mi et al. (Science, 2018)
Bibliography
A single-cell transcriptomic atlas of developing inhibitory neurons reveals expanding and contracting modes of diversification
Micoli, Elia; Restelli, Facundo Ferrero; Barbiera, Giulia; Moors, Rani; Nouboers, Evelien; Du, Jessica Xinyun; Bertels, Hannah; Liu, Minhui; Konstantopoulos, Dimitris; Takeoka, Aya; Lippi, Giordiano; Lim, Lynette.
bioRxiv, 2025. DOI: 10.1101/2025.02.19.636192
Research resources
Cortical somatostatin long-range projection neurons and interneurons exhibit divergent developmental trajectories.
Fisher, Josephine; Verhagen, Marieke; Long, Zhen; Moissidis, Monika; Yan, Yiming; He, Chenyi; Wang, Jingyu; Micoli, Elia; Alastruey, Clara Milían; Moors, Rani; Marín, Oscar; Mi, Da; Lim, Lynette.
Neuron, 2024. DOI: 10.1016/j.neuron.2023.11.013
Loss of Cntnap2 Causes Axonal Excitability Deficits, Developmental Delay in Cortical Myelination, and Abnormal Stereotyped Motor Behavior.
Scott, Ricardo; Sanchez-Aguilera, Alberto; van Elst, Kim; Lim, Lynette; Dehorter, Nathalie; Bae, Sung Eun; Bartolini, Giorgia; Peles, Elior; Kas, Martien JH; Bruining, Hilgo; Marin, Oscar.
Cerebral Cortex; 2019. DOI: 10.1093/cercor/bhx341
Development and Functional Diversification of Cortical Interneurons.
Lim, Lynette; Mi, Da; Llorca, Alfredo; Marin, Oscar.
Neuron, 2018. DOI: 10.1016/j.neuron.2018.10.009
Optimization of interneuron function by direct coupling of cell migration and axonal targeting.
Lim, Lynette; Pakan, Janelle MP; Selten, Martijn M; Marques-Smith, Andre; Llorca, Alfredo; Bae, Sung Eun; Rochefort, Nathalie L; Marin, Oscar.
Nature Neuroscience; 2018. DOI: 10.1038/s41593-018-0162-9
More than one way to induce a neuron.
Lim, Lynette; Marin, Oscar.
Nature, 2018. DOI: 10.1038/d41586-018-04978-5
Early emergence of cortical interneuron diversity in the mouse embryo.
Mi, Da; Li, Zhen; Lim, Lynette; Li, Mingfeng; Moissidis, Monika; Yang, Yifei; Gao, Tianliuyun; Hu, Tim Xiaoming; Pratt, Thomas; Price, David J; Sestan, Nenad; Marin, Oscar.
Science, 2018. DOI: 10.1126/science.aar6821
Tuning of fast-spiking interneuron properties by an activity-dependent transcriptional switch.
Dehorter, Nathalie; Ciceri, Gabriele; Bartolini, Giorgia; Lim, Lynette; del Pino, Isabel; Marin, Oscar.
Science, 2015. DOI: 10.1126/science.aab3415
STIM2 regulates PKA-dependent phosphorylation and trafficking of AMPARs.
Garcia-Alvarez, Gisela; Lu, Bo; Yap, Kenrick An Fu; Wong, Loo Chin; Thevathasan, Jervis Vermal; Lim, Lynette; Ji, Fang; Tan, Kia Wee; Mancuso, James J; Tang, Willcyn; Poon, Shou Yu; Augustine, George J; Fivaz, Marc.
Molecular Biology of the Cell, 2015. DOI: 10.1091/mbc.E14-07-1222
Lanosterol induces mitochondrial uncoupling and protects dopaminergic neurons from cell death in a model for Parkinson's disease.
Lim, Lynette; Jackson-Lewis, V; Wong, LC; Shui, GH; Goh, AXH; Kesavapany, S; Jenner, AM; Fivaz, M; Przedborski, S; Wenk, MR.
Cell Death and Differentiation, 2012. DOI: 10.1038/cdd.2011.105
A method for analysis of gene expression in isolated mouse photoreceptor and Muller cells.
Wahlin, K; Lim, Lynette; Grice, EA; Campochiaro, PA; Zack, DJ; Adler, R.
Molecular Vision, 2004.
Mapping hypoxia-induced bioenergetic rearrangements and metabolic signaling by 18O-assisted 31P NMR and 1H NMR spectroscopy.
Pucar, D; Dzeja, PP; Bast, P; Gumina, RJ; Drahl, C; Lim, Lynette; Juranic, N; Macura, S; Terzic, A.
Molecular And Cellular Biochemistry, 2004. DOI: 10.1023/b:mcbi.0000009875.30308.7a